How Does Nephrotic Syndrome Cause High Levels of BUN and Creatini

How Does Nephrotic Syndrome Cause High Levels of BUN and Creatini

For patients with Nephrotic Syndrome, they can have high levels of BUN and creatinine. Nephrotic Syndrome is a kind of kidney disease which is featured with much proteinuria, hypoproteinemia, serious edema and hyperlipemia. The fundamental cause of Nephrotic Syndrome is glomeruli damage. However, Bun and creatinine are some wastes in body. So how does Nephrotic Syndrome make these two wastes increase? Please see the below:

http://www.igancure.com/nephrotic-syndrome-symptoms-complications/557.html