IGA nephropathy high blood creatinine how to treat? The key to the treatment of kidney disease is to repair damaged cells, the only way to achieve a good therapeutic effect. So, IGA nephropathy, high blood creatinine how to treat it?IGA nephropathy is a glomerular mesangial area characterized by the predominance of IGA accumulation in glomerular disease. Most people before the onset of upper respiratory tract or gastrointestinal infections, a few hours or days after the onset of hematuria, local patients have general malaise, muscle and waist pain, sometimes showing dysuria and urinary frequency. Immunofluorescence showed IGA granular accumulation along the mesangial and capillary walls. The clinical manifestations of recurrent episodes of gross hematuria with or without proteinuria.
Simple hematuria such as timely, standard treatment is often a little better prognosis, and IGA nephropathy with a large number of proteinuria hematuria in patients with poor prognosis. Hematuria and (or) proteinuria is due to the accumulation of immune complexes to the glomerular basement membrane, causing glomerular ischemia and hypoxia, increased permeability of the basement membrane barrier, leading to red blood cells from these damaged basement membrane leakage .
Early kidney damage is no obvious clinical symptoms, with pathological damage more and more serious, renal ischemia and hypoxia, glomerular cells inherent in the beginning of proliferation, sclerosis, necrosis, renal fibrosis followed by attack, in turn Continue to promote the kidney cells and renal function of the inherent decline in a large number of toxins can not be promptly excreted in vitro accumulation of the body, resulting in the body of a series of toxic reactions, and then showed elevated serum creatinine, urea nitrogen increased, such as did not stop Timely and effective standard treatment, later will soon enter uremia!
From the IGA nephropathy, proteinuria, serum creatinine rise in the principle can be seen in the picture - IGA nephropathy will increase serum creatinine, occult blood, proteinuria will show behind the "manipulation of hand" is the kidney fibrosis, Kidney inherent cell damage, variation.
IGA nephropathy patients due to 5 years of medication do not understand the standard of treatment, systematic poor, had missed the optimal treatment of simple hematuria. As the lack of knowledge on the treatment of IGA nephropathy, choose the doctor do not understand, no targeted, but also failed to grasp only hematuria, proteinuria present, serum creatinine did not increase the inflammatory response to treatment opportunities. And now into the renal fibrosis constitute the period, elevated serum creatinine, the treatment process is the last chance to reverse the disease, the patient's treatment should be blocked from renal fibrosis and glomerular repair inherent cells, consolidate, multi-target Comprehensive treatment.
