People with a gene linked to weight gain are just as likely to benefit from weight loss programmes as those without, researchers have discovered. The findings suggest diet, exercise and drug-based approaches to losing weight can be widely beneficial, even if some people may have a greater risk of piling on the pounds due to their genetics. In short, your DNA is not a barrier to weight loss. While many genes are believed to affect body weight, a particular version of the so-called FTO gene shows one of the strongest associations with fat gain. Those carrying two copies of the genetic variant – about 16% of the population – are on average 3kg heavier than those without, and 1.7 times more likely to be obese. While it is not known exactly how the genetic variant promotes weight gain, it is believed to increase the appeal of high-calorie foods and reduce the feeling of fullness after a meal. But whether it also affects efforts to shed pounds has been a matter of debate. "It has become clear that genetics play a part in the reason why some of us get fatter," said John Mathers, lead author of the research from Newcastle University. "The one that has the biggest effect in most people is the FTO gene, so we wondered whether having the high-risk version of the FTO gene would affect how well you could lose weight." Writing in the British Medical Journal, Mathers and an international team of collaborators describe how they analysed eight previously published randomised control trials involving a total of more than 9,500 overweight or obese adults to investigate whether carrying the obesity-linked version of the FTO gene affects the ability to lose weight. In all of the studies, the participants were tested to discover whether they carried the genetic variant, and whether they had one copy or two, but the results were not disclosed to the participants. The researchers found that for each copy of the high-risk gene the participants possessed, they were, on average, almost 0.9kg heavier. TThe participants took part in a variety of weight-loss programmes, including diet-based, exercise-based and drug-based approaches. "To our surprise, we discovered that carrying the high-risk FTO gene made no difference to your ability to lose weight." "So people lost weight at just the same rate if they had the high-risk version of the FTO gene as if they didn't," said Mathers. "There was no link between the type of the intervention – so whether the people were losing weight through diet or physical activity – and the gene. It seemed to work equally well." Sex and ethnicity, the authors said, did not affect the rate of weight loss, although they noted there was a lack of participants of Asian descent. The studies, added Mathers, did not show whether carrying the obesity-linked version of the FTO gene affects whether weight loss was sustained, as the longest follow-up time was three years. Dr Jude Oben, co-founder of the Obesity Action Campaign and senior lecturer in hepatology at University College London, welcomed the results. "Obesity is costing the NHS 16bn pounds a year. We at Obesity Action Campaign are alarmed by this." "Obesity causes cancer, diabetes, heart disease and liver cirrhosis. It is the HIV of our age. It is killing millions of our patients," he said. "That this size of study and its robust statistical methodologies support common sense is great. " "It means that general weight loss strategies which must involve the psychological, nutritional, physical and policy changes should be developed."
Symptoms of Kidney Diseases Kidney is the root of one’s body, so everyone should protect it very carefully. But do you know the symptoms of kidney diseases? See as bellows: 1.Always feel tired. When there are some problems with your kidney, the metabolic waste cannot be eliminated from the urine. Thus, you may feel tired and languid. Some people may think the reason is overtired or other things, which may make them ignore the problems in their kidney. 2.Have no appetite and even feel nauseated. When people have those symptoms, some of them always think that there are something wrong with their stomach. They think it is nothing serious so that they put it aside. However, they do not know that may be the early symptoms of kidney disease, and even worse they may delay the best occasion for the treatment. 3.Foam in urine. There are many reasons of why there are foam in one’s urine. One reason is that there is protein leaking from kidney to the urine. 4.Low back pain. The location of the kidney is in two sides of the lumbar spine. So people may feel low back pain when they have kidney diseases. 5.Too much or too little urine a day. A health person urinates for four to six times a day and the urine volume is 800 to 2000 ml. If the volume is decrease or increase, there may be something wrong with ones kidney. 6.Swelling. If there is a sudden swelling of your eyelids, lower limbs or general pitting edema of your body, you must pay attention to whether you have kidney diseases or not. 7. Urine protein or urine occult blood. You’d better to take regular physical examinations. If you do have urine protein and urine occult blood in the routine urinalysis, you do remember to see a doctor in time. 8. Anemia. If we appear anemia, we will thinks about blood problem at once. But actually, kidney damage can also cause anemia. Because the function of kidney is not only to excrete body wastes but also to secrete Hematopoietic hormone. 9. Diabetes. Diabetic nephropathy is one of the most serious complications of diabetes. There are five stages of diabetic nephropathy. And it is efficient to receive the early treatment. Once it is too late, it will evolve into uremia. Therefore, patients with diabetes must take renal examinations frequently. 10. Hypertension. High blood pressure may lead to hypertensive nephropathy, so people with high blood pressure must be so careful. In fact, kidney diseases can also cause high blood pressure. So if you have high blood pressure, you should be careful enough if you got kidney disease. 11.Gout and hyperuricemia. Too much uric acid in blood lead to gout and hyperuricemia. The deposition of uric acid can damage the kidney. 12.Urinary tract infection. If you are often affected by Urinary tract infection that you should be careful. Because urinary tract infection may cause renal insufficiency. People may do not know it can lead to kidney disease. So when the final results have found, many people already have missed the best occasion for treatment because of the incomplete and delayed therapy in early treatment.
Turbid Urine Does not Mean Nephritis Some people discover that their urine turns cloudy, so they think nephritis begin attacking them. It is not the case. Cloudy urine may result from many reasons. If there are various kinds of white blood cells, red blood cells, grume, albumin, globulin or other kinds of protein in urine, the urine would become cloudy. Lymph in urine would also lead to turbid urine. After being vibrated, there would be some white or light yellow foams appear in normal and newly excreted urine. After short-term posput, urine becomes mildly turbid. This is because after cooling, there would be some evaporate materials separate out of urine. If the urine is alkaline, phosphate crystal and carbonate crystal would separate out, urine would becomes gray and turbid. If the urine is acidic, lihate crystal would separate out, urines would show red and turbid. Phosphate crystal and carbonate crystal would disappear when combining with acetic acid, lihate would also vanish when heating or combing with alkali, then urine would become limpid. So if urine would not become limpid after heating or adding acetic acid or alkali, people can consider that the cloudy urine result from lesion in kidney. From above, cloudy urine is not the indeed symptom of nephritis. But if people’s urine turns turbid and red , and there are lots of foams in urine, they’d better go to formal hospitals to take test.
Whether Play Taiji Could help the Recovery from Hypertensive Nephropathy The
Taiji culture in our country is profound. Every morning in our daily life, you
could see many Taiji lovers gathered together and play it. Many people advocated
that practice Taiji could fortify one’s health and cure different kinds of
diseases such as hypertensive nephropathy. So does Taiji really help to treat
hypertensive nephropathy? The kidney disease experts said that practice Taiji
indeed have the function of readjust the mental and physical health and
strengthen the body. Taiji could adjust the physiological state of our body, and
make the function of human body stay at “ relaxing reaction”. This kind of
reaction could adjust vegetative nervous system and decrease the activity of
sympathetic nerve through lower the metabolism. It could also help to change the
abnormal symptoms of the hypertensive nephropathy patients’ haemodynamics.
Practicing Taiji could also decrease the resistance surrounded us, and make the
blood pressure goes down, and improve the peripheral blood flow. At the same
time, doing Taiji may let the secretion of renin and angiotensin begin to
change, so that the level of angiotensin at ease and decrease the blood
pressure. So practice Taiji is helpful to prevent and cure diabetes and make the
disease condition better and stable through the guidance of thoughts and adjust
of breath. The sports that hypertensive nephropathy patients could choose are
waling, jogging, Taiji, Baduanjin exercises, health exercises and qigong. They
should not choose those sport items that are excessive exercises or waving
exaggerated and of high frequency. Such as take a walk everyday for those who
are elder and in heavier condition, they should control the time for they don’t
fell tired. The patients should better not do exercises outside in the early
morning, because the temperature outside is too low for them and would stimulate
the blood vessel shrinks. It may aggravate the diabetes condition and even cause
stroke. So the best time for hypertensive nephropathy patients to do exercises
is at 16:00 to 17:00 in the afternoon. The details above talks about that
practice Taiji is helpful to cure hypertensive nephropathy. But the patients of
hypertensive nephropathy should not be too tired, and they should also keep
warm, because it may sweat after doing exercises. They should prevent from cold,
because both catch a cold and overworking are easily aggravate state of
hypertensive nephropathy.
Keeping health life habits The kidney disease patient cannot stay up. The root reason is that staying up would lower immune power, which is the main trigger for the kidney disease. If you stay up, such symptoms as having a cold will appears. Staying up doesn’t matter for the health people, but the kidney disease patient may suffers the related damages. Apart from acute inflammation stage, appropriate exercise is advocated. How about the benefits of the exercise? Firstly, it can improve the immunity and avoid worsening or relapsing the condition. Secondly, exercise can activate blood vessels and control blood pressure and blood fat. Finally, keep a bright mood. Some patients regard the working even the manual labor as kinds of exercise. What the exercise we have mentioned above is the exercise in calm or bright mood. These series of activities can provide the parts of body mediate and continuous exercise, improving the body flexibility. The activities during the working time are rare to serve these functions. Therefore, we can count it as exercise. It is those who can control with themselves can make further in the process of fighting against disease.
What diseases are caused by kidney disease Kidney is an important organ, if kidney has problem, that must be serious, nowadays many people cause to the happen of kidney disease, it will influence our health. Therefore, we hope patients can get timely treatment, or it will cause to other diseases. I will introduce more details in the follow: 1 skin symptoms Boring, scaling, dull. some patients have darker skin, caused by diffuse melanin. Uremia discharged from the sweat glands, will be condensed into white crystals called "urea cream" , stimulating the skin so that it would cause to uremic dermatitis and skin itching (skin itching and secondary parathyroid hormone also have relations). 2 respiratory system performance Exhaled gas has the smell of urine, susceptible to bronchitis, pneumonia, pleurisy. Severe metabolic acidosis, can show Kusima big breath. Recognize the dangers of renal insufficiency so as to control kidney disease earlier. 3, cardiovascular systemic symptoms High blood pressure, myocardial damage, arrhythmia, and may have small arteries, retinal arteriosclerosis can affect the vision and retinal hemorrhage. In severe cases can show pericardial friction (fibrous pericarditis), the majority may have pericardial effusion, and even cardiac tamponade. The end of renal damage will be more serious, leading to the emergence of heart failure earlier. 4, Hematopoietic system kidney symptoms Severe anemia is an important symptom, patients in early stage will have bleeding tendency, often accompanied with subcutaneous ecchymosis, epistaxis, bleeding gums, or hematemesis, hematochezia, hematuria, intracranial hemorrhage, menstrual disorders, the majority may have pericardial hemorrhage.
Supper and fat According to statistics, 90% fat man is because that they take more and exercise less in the supper, excessive heat forms into fat under the function of insulin. So they become fatter and fatter. Supper and diabetes Long term over intake in supper, usually stimulate amounts of secret of insulin, which is easy to increase the burden of pancreas islet, accelerating its aging, further inducing diabetes, of course, fat will also induce diabetes. Supper and urine tract stone Body discharging calcium after 4-5 hours of supper, if take late on the supper, you have been in the sleeping when the body start discharging calcium. And then urine retain in the ureter, bladder, urine tract and can’t be discharged out of our body in time and causing the intake of calcium increasing, which is easy to deposit and form to crystals. Long-term deposition is easy to form to stone. Supper and high blood pressure If your supper is too fat, blood flowing rate becomes slow when sleeping, amounts of blood fat will deposit in the vascular wall. And then causing to shrink of arteriole and microscopic artery so that peripheral vascular resistance increases, make blood pressure is suddenly going up, accelerating the process of sclerosis Supper and fat liver Over eat in the supper,the concentration of blood sugar and fatty acid will accelerate the composition of fat, in addition, less activity in the evening also accelerate the transfer of fatty liver
Whether Play Taiji Could help the Recovery from Hypertensive Nephropathy The
Taiji culture in our country is profound. Every morning in our daily life, you
could see many Taiji lovers gathered together and play it. Many people advocated
that practice Taiji could fortify one’s health and cure different kinds of
diseases such as hypertensive nephropathy. So does Taiji really help to treat
hypertensive nephropathy? The kidney disease experts said that practice Taiji
indeed have the function of readjust the mental and physical health and
strengthen the body. Taiji could adjust the physiological state of our body, and
make the function of human body stay at “ relaxing reaction”. This kind of
reaction could adjust vegetative nervous system and decrease the activity of
sympathetic nerve through lower the metabolism. It could also help to change the
abnormal symptoms of the hypertensive nephropathy patients’ haemodynamics.
Practicing Taiji could also decrease the resistance surrounded us, and make the
blood pressure goes down, and improve the peripheral blood flow. At the same
time, doing Taiji may let the secretion of renin and angiotensin begin to
change, so that the level of angiotensin at ease and decrease the blood
pressure. So practice Taiji is helpful to prevent and cure diabetes and make the
disease condition better and stable through the guidance of thoughts and adjust
of breath. The sports that hypertensive nephropathy patients could choose are
waling, jogging, Taiji, Baduanjin exercises, health exercises and qigong. They
should not choose those sport items that are excessive exercises or waving
exaggerated and of high frequency. Such as take a walk everyday for those who
are elder and in heavier condition, they should control the time for they don’t
fell tired. The patients should better not do exercises outside in the early
morning, because the temperature outside is too low for them and would stimulate
the blood vessel shrinks. It may aggravate the diabetes condition and even cause
stroke. So the best time for hypertensive nephropathy patients to do exercises
is at 16:00 to 17:00 in the afternoon. The details above talks about that
practice Taiji is helpful to cure hypertensive nephropathy. But the patients of
hypertensive nephropathy should not be too tired, and they should also keep
warm, because it may sweat after doing exercises. They should prevent from cold,
because both catch a cold and overworking are easily aggravate state of
hypertensive nephropathy.